Book direct
and save up to 10%
compared to Booking.com
Check rooms and rates
From190US$ /night
Check-in
26Oct2025Select date
Check-out
27Oct2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview

425 South Second Street, Minneapolis, Minnesota, United States, 55401

Residence Inn Minneapolis Downtown At The Depot - Extended-stay hotel with fitness center near St Anthony Falls

Located in Downtown West on the banks of the Mississippi River, this hotel is a short walk from Mill Ruins Park, Saint Anthony Falls, and a metro station. The property features a fitness center with 14 mounted TVs, aerobic and anaerobic equipment, and a water bottle filling station. On-site dining includes Milwaukee Road restaurant serving Midwestern cuisine and Stone Arch Bar offering cocktails. Guests have access to an indoor pool, hot tub, and free Wi-Fi in communal areas. The hotel is 11 miles from Mall of America and within walking distance of Target Field, Target Center, and US Bank Stadium.

Additional perks of the hotel

Free breakfast buffet served weekdays from 6:30 AM to 9:00 AM

Complimentary reception on select days

Dry cleaning/laundry services

On-site parking available for a fee

Pet-friendly with a maximum weight limit of 150 lbs

Accessible features include elevators and service animal accommodations

Rooms

All 131 rooms are apartment-style suites with kitchens, refrigerators, and stovetops. Each room includes a 32-inch LCD TV with premium channels, premium bedding, and laptop-friendly workspaces. Separate sitting areas and air conditioning are provided. Private bathrooms feature a bath or shower.

Other conveniences

Free local calls

Ironing facilities

Digital check-in service

Mobile key access

Complimentary coffee/tea

View all

Choose Your Room

Our listed hotels offer a variety of room types—double rooms, family suites, or deluxe options—all with features like breakfast, flexible cancellation policies, and exclusive deals.
Queen Studio Sofa Bed
2 persons
37 m² 
1 King-size bed
Heating
Air conditioning
One-Bedroom Queen Suite Sofa Bed
2 persons
42 m² 
1 King-size bed
Heating
Air conditioning
Two-Bedroom Queen Suite Sofa Bed
2 persons
56 m² 
1 King-size bed
Heating
Air conditioning

Room Rates & Availability Tracker

Find Deals for Your Travel Dates

Transportation Tips

Transportation Options

City Centre
Minneapolis200 m
Airports
Minneapolis-Saint Paul International (MSP) 16.0 km
Gorno-Altaysk (rgk) 87.4 km
Train
Target Field Station \x26 Rail Platform 1.3 km
Minneapolis Sculpture Garden 2.6 km
Bus
Bus stop200 m

Amenities

Thoughtful hotel amenities for a comfortable stay

General

  • Non-smoking rooms
  • Internet access
  • Parking
  • 24-hour reception
  • Pets allowed

Sports & Fitness

  • Fitness centre

Services

  • Grocery shopping service

Dining

  • Restaurant
  • Bar/ Lounge area

Children

  • Video games

Spa & Leisure

  • Indoor swimming pool

Room features

  • Air conditioning
  • Sitting area
  • Ironing facilities

Media

  • Flat-screen TV
Show more

Hotel Location

425 South Second Street, Minneapolis, Minnesota, United States, 55401
Map view
425 South Second Street, Minneapolis, Minnesota, United States, 55401
Nearby
Museum
Mill City Museum
380 m
Theatre
Guthrie Theater
500 m
West River Road and Portland Ave
St Anthony Falls Heritage Trail
330 m
1 Portland Ave
Upper St. Anthony Lock and Dam
380 m
Event hall
The Armory
560 m
Public Building
Minneapolis City Hall
440 m
Park
Mill Ruins Park
330 m
Saint Anthony Main
Water Power Park
530 m
Minneapolis
Lake Nokomis
380 m
Minneapolis
Mississippi Mile
270 m
Restaurants
Smith & Porter Restaurant + Bar
20 m
428 S 2nd St
Crooked Pint Ale House
240 m
501 South Washington Avenue
Milwaukee Road
230 m
225 3rd Ave S Renaissance Minneapolis Hotel
Zen Box Izakaya
320 m
602 Washington Ave S
Twins Grill
380 m
4354-4382 Glumack Dr MSP Airport
Sawatdee
400 m
607 Washington Ave S
Bar Zia
490 m
420 S 4th St South 4th street and 5th avenue
McKinney Roe
550 m
530 S 4th St
Kindee Thai Restaurant
440 m
719 S 2nd St
Bus Stop Burgers and Brewhouse
690 m
620 South 4th Street Suite 130
Giulia
600 m
412 S 4th St at the Emery Hotel
Restaurant Max
1.2 km
215 S 4th St The Hotel Minneapolis
Unlock Early Booking Discounts
Grab Your Special Rates Today!
Check Rates

Next best alternative

Consider them for your next trip.

Inspiration for future getaways

Good Hotel alternatives
Check-in
26Oct2025Select date
Check-out
27Oct2025Select date
Rooms and Guests2 Guests, 1 Room